Ribociclib acetate

• Description :

  Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic[1].

• CAS Number :

  [2762182-61-4]

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ribociclib-acetate.html

• Solubility :

  DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2)O

• Molecular Formula :

  C21H25N7O2

• Molecular Weight :

  407.47

• References & Citations :

  [1]Sahu AK, et al. Identification and structural characterization of potential degraded impurities of ribociclib by time of flight -tandem mass spectrometry, and their toxicity prediction. J Pharm Biomed Anal. 2021 Apr 15;197:113933.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported