Ribociclib acetate

• Description:

  Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic[1].

• UNSPSC:

  12352005

• Target:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ribociclib-acetate.html

• Solubility:

  DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2)O

• Molecular Formula:

  C21H25N7O2

• Molecular Weight:

  407.47

• References & Citations:

  [1]Sahu AK, et al. Identification and structural characterization of potential degraded impurities of ribociclib by time of flight -tandem mass spectrometry, and their toxicity prediction. J Pharm Biomed Anal. 2021 Apr 15;197:113933.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2762182-61-4]