p38-α MAPK-IN-1

p38-α MAPK-IN-1

• CAS Number: 443913-15-3
• UNSPSC Description: p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].
• Target Antigen: Autophagy; p38 MAPK
• Type: Reference compound
• Related Pathways: Autophagy;MAPK/ERK Pathway
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/p38-_alpha__MAPK-IN-1.html
• Purity: 99.89
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC1=CC=C(N2C(NC(NC3=CC=C(OCCN4CCOCC4)C=C3)=O)=CC(C(C)(C)C)=N2)C=C1
• Molecular Weight: 477.60
• References & Citations: [1]Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported