ML-216

CAT: 0026-B2666-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B2666-25Size:25 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML-216 is a potent and selective inhibitor of BLM (Bloom) helicase (IC₅₀ = 1.8 μM); it displays 28-fold selectivity against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s ≥ 50 μM). At 25-50 μM, ML-216 has been shown to dose-dependently inhibit the proliferation of BLM-expressing PSNF5 fibroblast cells but not BLM-deficient PSNG13 fibroblast cells.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months