Products for Research Use Only

ML-193

CAT: 0026-B3016-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B3016-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML-193 is a selective quinoline aryl sulfonamide antagonist for GPR55, a lysophosphatidylinositol (LPI)-sensitive receptor that is also involved in cannabinoid signaling. It inhibits GPR55 with an IC₅₀ of 221 nM. It also inhibits GPR55-dependent ERK phosphorylation with an IC₅₀ of 65 nM and blocks translocation of PKC βII. Pretreatment with ML-193 (1 μg/0.5 μl, 15 min before LPI), antagonized the LPI-induced nociception in a rat model.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months