Products for Research Use Only
RegisterLogin

(S, S) -TAK-418

CAT: 0804-HY-138830A-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-138830A-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(S, S) -TAK-418 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), demonstrating significant normalization of aberrant gene expression in neurodevelopmental disorders. (S, S) -TAK-418 also ameliorates ASD-like behaviors in rodent models affected by maternal exposure to valproate or poly I:C. (S, S) -TAK-418 modulates gene expression differently across various models and ages, indicating its potential as a therapeutic agent for conditions like autism spectrum disorder and schizophrenia.
CAS Number
1818253-48-3
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-s-tak-418.html
Smiles
O=C(NC1CCOCC1)C2=CSC([C@@H](C3)[C@H]3NCC4CC4)=C2.Cl
Molecular Formula
C17H25ClN2O2S
Molecular Weight
356.91
References & Citations
[1]LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-138830-01TAK-418
HY-14314ABT-418
HY-108718G-418
HY-13787XL-418
HY-W953620CRBN ligand-418
HY-105170B-01ABT-418 (hydrochloride)
HY-17561-01G-418 (disulfate)
HY-117850TAK 187
HY-105168TAK 044
HY-16475-01TAK-441

Alternative Products

CatalogName
M35103-01TAK-418
GTR19198330-01ABT-418
C04219G-418
T69574-01TRA 418
T68477-01XL-418
6889/50ML 418
T10224-01ABT-418 hydrochloride
T6512-01G-418 disulfate
ANTY021115Src(Ab-418)
BIG0175-01G-418 Disulphate

Popular Products