(S,S)-TAK-418

• UNSPSC Description:

  (S,S)-TAK-418 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), demonstrating significant normalization of aberrant gene expression in neurodevelopmental disorders. (S,S)-TAK-418 also ameliorates ASD-like behaviors in rodent models affected by maternal exposure to valproate or poly I:C. (S,S)-TAK-418 modulates gene expression differently across various models and ages, indicating its potential as a therapeutic agent for conditions like autism spectrum disorder and schizophrenia.

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/s-s-tak-418.html

• Smiles:

  O=C(NC1CCOCC1)C2=CSC([C@@H](C3)[C@H]3NCC4CC4)=C2.Cl

• Molecular Weight:

  356.91

• References & Citations:

  [1]LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1818253-48-3