NIT

• Description:

  NIT is an inhibitor of HIV-1 protease (HIV-1p) with Ki values of 96 and 91 μM for WT HIV-1p and MDR HIV-1p, respectively[1].

• UNSPSC:

  12352005

• Target:

  HIV Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/nit.html

• Smiles:

  O=C1N(C2=CC=C3NC(SC3=C2)=S)C(C4=C1C=CC=C4[N+]([O-])=O)=O

• Molecular Formula:

  C15H7N3O4S2

• Molecular Weight:

  357.36

• References & Citations:

  [1]Ung PM, et al. An allosteric modulator of HIV-1 protease shows equipotent inhibition of wild-type and drug-resistant proteases. J Med Chem. 2014 Aug 14;57 (15) :6468-78.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [299922-10-4]