NIT

• Description :

  NIT is an inhibitor of HIV-1 protease (HIV-1p) with Ki values of 96 and 91 μM for WT HIV-1p and MDR HIV-1p, respectively[1].

• CAS Number :

  [299922-10-4]

• UNSPSC :

  12352005

• Target :

  HIV Protease

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/nit.html

• Smiles :

  O=C1N(C2=CC=C3NC(SC3=C2)=S)C(C4=C1C=CC=C4[N+]([O-])=O)=O

• Molecular Formula :

  C15H7N3O4S2

• Molecular Weight :

  357.36

• References & Citations :

  [1]Ung PM, et al. An allosteric modulator of HIV-1 protease shows equipotent inhibition of wild-type and drug-resistant proteases. J Med Chem. 2014 Aug 14;57 (15) :6468-78.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported