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NIT

CAT: 0804-HY-124360Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124360Size:1 Each
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Description
NIT is an inhibitor of HIV-1 protease (HIV-1p) with Ki values of 96 and 91 μM for WT HIV-1p and MDR HIV-1p, respectively[1].
CAS Number
299922-10-4
UNSPSC
12352005
Target
HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nit.html
Smiles
O=C1N(C2=CC=C3NC(SC3=C2)=S)C(C4=C1C=CC=C4[N+]([O-])=O)=O
Molecular Formula
C15H7N3O4S2
Molecular Weight
357.36
References & Citations
[1]Ung PM, et al. An allosteric modulator of HIV-1 protease shows equipotent inhibition of wild-type and drug-resistant proteases. J Med Chem. 2014 Aug 14;57 (15) :6468-78.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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