NITD-688

• Description:

  NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. NITD-688 can be used in the research of dengue virus (DENV) [1].

• Product Name Alternative:

  EYU-688

• UNSPSC:

  12352005

• Target:

  Dengue Virus; Flavivirus; Virus Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/nitd-688.html

• Concentration:

  10mM

• Purity:

  98.04

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  N#CC (C (CN1CC2CCCCC2) =C (CC (C) 1C) S3) =C3NC (CC (C=C4) =CC=C4[S] (N) (=O) =O) =O

• Molecular Formula:

  C25H32N4O3S2

• Molecular Weight:

  500.68

• References & Citations:

  [1]Moquin SA, et al. NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models. Sci Transl Med. 2021 Feb 3;13 (579) :eabb2181.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2407227-31-8