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CGS 8216

CAT: 0804-HY-121116-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121116-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGS 8216 is a non-benzodiazepine brain benzodiazepine receptor ligand that binds to rat forebrain membranes with high affinity and specificity. CGS 8216 also inhibits 3H-flunitrazepam (3H-FLU) binding to rat synaptosomal membranes and blocks 3H-FLU labeling of brain benzodiazepine receptors in vivo with potency equivalent to Diazepam[1].
CAS Number
77779-60-3
UNSPSC
12352005
Target
GABA Receptor
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgs-8216.html
Purity
99.85
Smiles
O=C1N(C2=CC=CC=C2)N=C3C1=CNC4=C3C=CC=C4
Molecular Formula
C16H11N3O
Molecular Weight
261.28
References & Citations
[1]Czernik A J, Petrack B, Kalinsky H J, et al. CGS 8216: Receptor binding characteristics of a potent benzodiazepine antagonist[J]. Life sciences, 1982, 30 (4) : 363-372.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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