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CGS 15435

CAT: 0804-HY-100283Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100283Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGS 15435, a potent thromboxane (TxA2) synthetase inhibitor with an IC50 of 1 nM, has a selectivity for Tx synthetase 100000-fold greater than that for cyclooxygenase, PGI2 synthetase and lipoxygenase enzymes.
CAS Number
[95853-92-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/CGS_15435.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCCC1=C(C2=CC=CN=C2)N(C)C3=C1C=C(Cl)C=C3
Molecular Formula
C20H21ClN2O2
Molecular Weight
356.85
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Olson RW, et al. CGS 15435A, a thromboxane synthetase inhibitor with an extended duration of action: a comparison with dazoxiben. Eur J Pharmacol. 1987 Jan 20;133 (3) :265-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TXA2/TP

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A20359-100CGS 15435 100mg
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A20359-200CGS 15435 200mg

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