OB-1

CAT: 0804-HY-122671-01Size: 5 mgDry Ice: NoHazardous: No

CAT#:0804-HY-122671-01Size:5 mg

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AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

OB-1 is a stomatin-like protein-3 (STOML3) oligomerization blocker. OB-1 is an effective inhibitor of the self-association of Stomatin, STOML1 and STOML2, but not podocin[1].

CAS Number

[300803-69-4]

UNSPSC

12352005

Target

SPFH Protein Superfamily

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ob-1.html

Purity

99.12

Solubility

DMSO : 12.73 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=C(C2=CC=CC=C2)OC3=CC=C(OC4=C([N+]([O-])=O)N=CN4C)C=C13)OCC

Molecular Formula

C21H17N3O6

Molecular Weight

407.38

References & Citations

[1]Wetzel C, et al. Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity. Nat Neurosci. 2017 Feb;20 (2) :209-218.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Stomatin

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