OB-1

• Description :

  OB-1 is a stomatin-like protein-3 (STOML3) oligomerization blocker. OB-1 is an effective inhibitor of the self-association of Stomatin, STOML1 and STOML2, but not podocin[1].

• UNSPSC :

  12352005

• Target :

  SPFH Protein Superfamily

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ob-1.html

• Purity :

  99.12

• Solubility :

  DMSO : 12.73 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=C(C2=CC=CC=C2)OC3=CC=C(OC4=C([N+]([O-])=O)N=CN4C)C=C13)OCC

• Molecular Formula :

  C21H17N3O6

• Molecular Weight :

  407.38

• References & Citations :

  [1]Wetzel C, et al. Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity. Nat Neurosci. 2017 Feb;20 (2) :209-218.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Stomatin

• CAS Number :

  [300803-69-4]