Boc-AEVD-CHO

• Description :

  Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases[1][2].

• UNSPSC :

  12352209

• Target :

  Apoptosis; Caspase

• Type :

  Peptides

• Related Pathways :

  Apoptosis

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/boc-aevd-cho.html

• Purity :

  98.34

• Solubility :

  DMSO : 66.67 mg/mL (ultrasonic)

• Smiles :

  C[C@H](NC(OC(C)(C)C)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O

• Molecular Formula :

  C22H36N4O10

• Molecular Weight :

  516.54

• References & Citations :

  [1]Garcia-Calvo M, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273 (49) :32608-13.|[2]Grassmé H, et al. Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene. 2003 Aug 21;22 (35) :5457-70.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [220094-15-5]