YVAD-CHO

• UNSPSC Description:

  YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor that can partially delay motoneurone death in lesioned facial nerve mice[1].

• Target Antigen:

  Caspase; Interleukin Related

• Type:

  Peptides

• Related Pathways:

  Apoptosis;Immunology/Inflammation

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/yvad-cho.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C=O)=O)=O)[C@H](CC1=CC=C(C=C1)O)N

• Molecular Weight:

  450.49

• References & Citations:

  [1]de Bilbao F, Dubois-Dauphin M. Acute application of an interleukin-1 beta-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death. Neuroreport. 1996 Nov 25;7(18):3051-4.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  153604-27-4