LDN-193189

CAT: 0026-B3067-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B3067-25Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
LDN-193189 inhibits the activity of the Bone Morphogenetic Protein (BMP) type I receptors ALK2 and ALK3 with IC₅₀ values of 5 nM and 30 nM respectively and shows weaker effects on activin and the TGF-β type I receptors ALK4, ALK5 and ALK7 (IC₅₀≥ 500 nM). It inhibits the activation of the BMP signaling effectors SMAD1, SMAD5 and SMAD8 in a dose-dependent manner in C2C12 cells. LDN-193189 significantly reduces tumor growth in SCID mice bearing MDA-PCa-118b tumors.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

Related Products

CatalogName
2016-25LDN-57444
2016-5LDN-57444
B2641-5LDN-212854
B2641-1LDN-212854
B3285-5LDN-192960 hydrochloride
B3285-25LDN-192960 hydrochloride

Alternative Products

CatalogName
MBS576391LDN-193189
TB6053-GMP/10LDN 193189
C17967LDN-193189 Dihydrochloride
S7507-5mgLDN-193189 2HCl
TRC-P480132-25MGLDN 193189-d8
ENZ-CHM327-0010LDN-193189 . dihydrochloride
HY-12071B-01LDN-193189 (dihydrochloride)
MBS578723LDN-193189 hydrochloride
bs-83010C-01LDN-193189 HCl
MF-0098125-01LDN-193189 Tetrahydrochloride

Popular Products