LDN-212854

• Description:

  LDN-212854 is a potent ALK inhibitor (IC₅₀ values are 1.3, 2.4, 85.8, 2,133 and 9,276 nM for ALK2, ALK1, ALK3, ALK4 and ALK5, respectively). Displays selectivity for ALK2 over ALK4 and ALK5 in cellular assays. Also exhibits activity against RIPK2, ABL1 and PDGFR-β (IC₅₀ values < 100 nM).

• Shipping Conditions:

  Gel Pack

• Storage Conditions:

  -20ºC

• Shelf Life:

  36 months