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LDN-193189 HCl

CAT: 0498-bs-83010C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83010C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LDN-193189 HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripotent stem cells.2-3 LDN-193189 HCl has also been used to examine the role of osteogenesis in prostate tumor metastases in bone.4
Conjugation
Unconjugated
Buffer
Orange-yellow solid
Storage Conditions
-20°C