VEGFR-2-IN-45

• UNSPSC Description:

  VEGFR-2-IN-45 (compound 3j) is a potent inhibitor of VEGFR-2, with the IC50 of 0.2 μM. VEGFR-2-IN-45 plays an important role in cancer research[1].

• Target Antigen:

  VEGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/vegfr-2-in-45.html

• Smiles:

  O=C(N1C2=CC=C(S(=O)(NC3=NC=CC=N3)=O)C=C2)/C(N=C1C4=CC=C(Cl)C=C4)=C/C5=CC=C(N(C)C)C=C5

• Molecular Weight:

  559.04

• References & Citations:

  [1]Manar R, et al. Insight on Some Newly Synthesized Trisubstituted Imidazolinones as VEGFR-2 Inhibitors. ACS Med. Chem. Lett. MAY 20, 2024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported