Galectin-3/galectin-8-IN-1
CAT:
804-HY-155191-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Galectin-3/galectin-8-IN-1
- UNSPSC Description: Galectin-3/galectin-8-IN-1 (Compound 53) is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 4.12 μM and 6.04 μM respectively. Galectin-3/galectin-8-IN-1 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-1 can be used for research of cancer and tissue fibrosis[1].
- Target Antigen: Galectin
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/galectin-3-galectin-8-in-1.html
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(C(N1)=CC2=C1C=CC(OC3=CC=C(Cl)C(Cl)=C3)=C2)NS(=O)(C4=CC=C5N=CSC5=C4)=O
- Molecular Weight: 518.39
- References & Citations: [1]Haoming Zhang, et al. Discovery of N-Arylsulfonyl-Indole-2-Carboxamide Derivatives as Galectin-3 and Galectin-8 C-Terminal Domain Inhibitors. ACS Med. Chem. Lett. 2023, 14, 9, 1257-1265.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported