Galectin-8-IN-1

• UNSPSC Description:

  Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N), with a Kd of 48 μM and 15-fold selectivity over galectin-3 and even better selectivity over the other mammalian galectins.

• Target Antigen:

  Galectin

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/galectin-8-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@@H](CO)OC=C[C@H]1OCC2=NC3=C(C=C(C(O)=O)C=C3)N2C

• Molecular Weight:

  334.32

• References & Citations:

  [1]Hassan M, et al. Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. ACS Med Chem Lett. 2021 Nov 2;12(11):1745-1752.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3028946-23-5