Galectin-8-IN-1

• Description :

  Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N), with a Kd of 48 μM and 15-fold selectivity over galectin-3 and even better selectivity over the other mammalian galectins.

• UNSPSC :

  12352005

• Target :

  Galectin

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/galectin-8-in-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@H]1[C@@H](CO)OC=C[C@H]1OCC2=NC3=C(C=C(C(O)=O)C=C3)N2C

• Molecular Formula :

  C16H18N2O6

• Molecular Weight :

  334.32

• References & Citations :

  [1]Hassan M, et al. Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. ACS Med Chem Lett. 2021 Nov 2;12 (11) :1745-1752.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Galectin-8

• CAS Number :

  [3028946-23-5]