Anti-MHC Class I (α+β2m chains) Alexa Fluor® 488

• Description:

  HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence.

• Certification:

  RUO

• Immunogen:

  Bovine lymphocytes

• Target Antigen:

  MHC Class I (α+β2m chains)

• Clone:

  IVA26

• Applications:

  FC (QC tested)

• Concentration:

  0.5 mg/mL

• Format:

  Alexa Fluor® 488

• Buffer:

  Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Storage Conditions:

  Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

• Specificity:

  The mouse monoclonal antibody IVA26 recognizes an extracellular epitope on MHC class I (alpha + beta2m chains) expressed in various animals.

• Applications Notes:

  Flow cytometry: Recommended dilution: 1-4 µg/ml

• Species:

  Mouse, Pig, Cow, Human, Rabbit, Sheep, Coturnix japonica

• CAS Number:

  9007-83-4

• Isotype:

  Mouse IgG1