Anti-HLA Class I Biotin

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CAT:

270-1B-422-C100

Size:

0.1 mg

Price:

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Anti-HLA Class I Biotin

Background: HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
Specifications: The antibody W6/32 recognises an extracellular epitope of MHC Class I molecules (MHC Class Ia) that are expressed on the surface of all human nucleated cell types. The antibody W6/32 is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody W6/32 is also suitable as a positive control for HLA tissue typing and crossmatching.
Certification: RUO
Host: Mouse
Species Reactivity: Cow, Non-human primates, Human, Cat
Negative Species: Rabbit
Immunogen: Membrane of human tonsil cells
Target Antigen: HLA Class I
Isotype: IgG2a
Clone: W6/32
Applications: Flow cytometry: Recommended dilution: 1-12 µg/mL
Validated Applications: FC, IP, IHC-F, ICC, ELISA
Concentration: 1 mg/mL
Format: Biotin
Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations: *Kievits F, Ivanyi P: Monomorphic anti-HLA monoclonal antibody (W6/32) recognizes polymorphic H-2 heavy-chain determinants exposed by association with bovine or human but not murine beta 2-microglobulin.Hum Immunol. 1987 Oct20(2):115-26.
Storage Conditions: Store at 2-8°C. Do not freeze.

Complementary Product Range

Our range of products, including Anti-HLA Class I Biotin, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

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1B-422-C100	Anti-HLA Class I Biotin
1B-422-C025	Anti-HLA Class I Biotin
1P-242-C025	Anti-HLA Class I PE
1P-363-C025	Anti-HLA Class I PE
1P-363-C100	Anti-HLA Class I PE
1P-422-C025	Anti-HLA Class I PE
1P-422-C100	Anti-HLA Class I PE
11-242-C025	Anti-HLA Class I Purified
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11-363-C100	Anti-HLA Class I Purified