Anti-STAT1 Purified

• Clone:

  SM2

• Format:

  Purified

• Buffer:

  Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• References & Citations:

  *Hubackova S, Krejcikova K, Bartek J, Hodny Z: Interleukin 6 signaling regulates promyelocytic leukemia protein gene expression in human normal and cancer cells. J Biol Chem. 2012 Aug 3;287 (32) :26702-14. , URL: https://www.ncbi.nlm.nih.gov/pubmed/22711534 , *Hubackova S, Kucerova A, Michlits G, Kyjacova L, Reinis M, Korolov O, Bartek J, Hodny Z: IFNγ induces oxidative stress, DNA damage and tumor cell senescence via TGFβ /SMAD signaling-dependent induction of Nox4 and suppression of ANT2. Oncogene. 2016 Mar 10;35 (10) :1236-49., URL: https://pubmed.ncbi.nlm.nih.gov/25982278/

• Other References:

  *Kovarik P, Stoiber D, Eyers PA, Menghini R, Neininger A, Gaestel M, Cohen P, Decker T: Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway. Proc Natl Acad Sci U S A. 1999 Nov 23;96 (24) :13956-61., URL: https://www.ncbi.nlm.nih.gov/pubmed/10570180?ordin, *Frank DA: STAT signaling in the pathogenesis and treatment of cancer. Mol Med. 1999 Jul;5 (7) :432-56., URL: https://www.ncbi.nlm.nih.gov/pubmed/10449805?ordin, *Bromberg J, Darnell JE Jr: The role of STATs in transcriptional control and their impact on cellular function. Oncogene. 2000 May 15;19 (21) :2468-73., URL: https://www.ncbi.nlm.nih.gov/pubmed/10851045?ordin, *Soond SM, Townsend PA, Barry SP, Knight RA, Latchman DS, Stephanou A: ERK and the E3 ubiquitin ligase beta TRCP targets STAT1 for degradation. J Biol Chem. 2008 Mar 31, URL: https://www.ncbi.nlm.nih.gov/pubmed/18378670?ordin