Anti-Hu Ig Lambda Light Chain Purified

• Background:

  Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.

• Specifications:

  The antibody Rs4 reacts with lambda light chains (22.5 kDa) of human immunoglobulin.

• CAS Number:

  9007-83-4

• Certification:

  RUO

• Host:

  Mouse

• Species Reactivity:

  Human

• Target Antigen:

  Ig Lambda Light Chain

• Isotype:

  IgG1

• Clone:

  Rs4

• Validated Applications:

  ICC, ELISA, WB

• Concentration:

  1 mg/mL

• Format:

  Purified

• Buffer:

  Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• References & Citations:

  *Filatov AV, Shmigol IB, Sharonov GV, Feofanov AV, Volkov Y: Direct and indirect antibody-induced TX-100 resistance of cell surface antigens. Immunol Lett. 2003 Feb 385(3):287-95. , URL: https://www.ncbi.nlm.nih.gov/pubmed/12663145,

• Other References:

  *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975194:77-95., URL: https://www.ncbi.nlm.nih.gov/pubmed/47690?ordinalp,

• Storage Conditions:

  Store at 2-8°C. Do not freeze.