Anti-Hu Ig Lambda Light Chain APC

• Description :

  Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa) . Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.

• Certification :

  RUO

• Negative Species :

  Rabbit, Hamster, Sheep, Guinea pig, Goat

• Reactivity :

  Human

• Target Antigen :

  Ig Lambda Light Chain

• Clone :

  4C2

• Applications :

  FC (QC tested)

• Format :

  APC

• Buffer :

  Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• References & Citations :

  *Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjø nnfjord GE, Bogen B, Munthe LA: Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013 Aug 15;4 (3) :566-77., URL: https://www.ncbi.nlm.nih.gov/pubmed/23933259

• Other References :

  *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh) . 1975;194:77-95., URL: https://www.ncbi.nlm.nih.gov/pubmed/47690?ordinalp

• Storage Conditions :

  Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

• Specificity :

  The antibody 4C2 reacts with lambda light chains (22.5 kDa) of human immunoglobulin.

• Applications Notes :

  6

• Isotype :

  Mouse IgG1