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Anti-Hu Ig Lambda Light Chain APC

CAT: 0270-1A-505-T100Size: 100 TestsDry Ice: NoHazardous: No
CAT#:0270-1A-505-T100Size:100 Tests
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa) . Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
Certification
RUO
Negative Species
Rabbit
,
Hamster
,
Sheep
,
Guinea pig
,
Goat
Reactivity
Human
Target Antigen
Ig Lambda Light Chain
Clone
4C2
Applications
FC (QC tested)
Format
APC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjø nnfjord GE, Bogen B, Munthe LA: Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013 Aug 15;4 (3) :566-77., URL: https://www.ncbi.nlm.nih.gov/pubmed/23933259
Other References
*Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh) . 1975;194:77-95., URL: https://www.ncbi.nlm.nih.gov/pubmed/47690?ordinalp
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The antibody 4C2 reacts with lambda light chains (22.5 kDa) of human immunoglobulin.
Applications Notes
6
Isotype
Mouse IgG1

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