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Anti-Hu Ig Lambda Light Chain PE

CAT:
270-1P-673-T100
Size:
100 Tests
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Anti-Hu Ig Lambda Light Chain PE - image 1

Anti-Hu Ig Lambda Light Chain PE

  • Background: Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
  • Specifications: The mouse monoclonal antibody 1-155-2 recognizes lambda light chains (22.5 kDa) of human immunoglobulin.
  • CAS Number: 9007-83-4
  • Certification: RUO
  • Host: Mouse
  • Species Reactivity: Human
  • Immunogen: Human IgA1 lambda myeloma protein
  • Target Antigen: Ig Lambda Light Chain
  • Isotype: Igg1 κ
  • Clone: 1-155-2
  • Applications: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 mL) is sufficient for 100 tests. Extracellular and intracellular staining.
  • Validated Applications: FC
  • Format: PE
  • Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
  • References & Citations: *Kubagawa H, Gathings WE, Levitt D, Kearney JF, Cooper MD: Immunoglobulin isotype expression of normal pre-B cells as determined by immunofluorescence. J Clin Immunol. 1982 Oct2(4):264-9., URL: https://www.ncbi.nlm.nih.gov/pubmed/6815220,*Bahler DW, Pindzola JA, Swerdlow SH: Splenic marginal zone lymphomas appear to originate from different B cell types. Am J Pathol. 2002 Jul161(1):81-8., URL: https://pubmed.ncbi.nlm.nih.gov/12107092/,*Tierens AM, Holte H, Warsame A, Ikonomou IM, Wang J, Chan WC, Delabie J: Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type. Haematologica. 2010 Aug95(8):1334-41., URL: https://www.ncbi.nlm.nih.gov/pubmed/20145271,
  • Other References: *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975194:77-95., URL: https://www.ncbi.nlm.nih.gov/pubmed/47690?ordinalp,
  • Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.