DFF45 (Cleaved-Thr225) rabbit pAb

• Background:

  Function:Inhibitor of the caspase-activated DNase (DFF40) ., PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 CIDE-N domain., subunit:Heterodimer of DFFA and DFFB.

• Description:

  Function: Inhibitor of the caspase-activated DNase (DFF40). PTM: Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 CIDE-N domain. subunit: Heterodimer of DFFA and DFFB.

• UniProt:

  O00273

• Swiss Prot:

  O00273

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human DFF45 (Cleaved-Thr225)

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:1000-2000 ELISA 1:5000-20000

• Molecular Weight:

  12 36kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  12 36kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm.

• Other Product Names:

  DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD)

• Gene ID (Human):

  1676