NT1-014B

CAT: 0804-HY-137500-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-137500-01Size:5 mg
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Description
NT1-014B is a tryptamine-derived lipidoid. NT1-014B incorporates NT-lipidoid into BBB-impermeable lipid nanoparticles (LNPs), enabling the LNPs to cross the BBB. NT1-014B enhances brain delivery via intravenous injection. NT1-014B can be used in ischemic stroke research[1][2].
CAS Number
[2739805-64-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Biochemical Assay Reagents; Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/nt1-014b.html
Concentration
10mM
Purity
98.43
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(CCN(CCC(OCCSSCCCCCCCCCC)=O)CCC1=CNC2=C1C=CC=C2)OCCSSCCCCCCCCCC
Molecular Formula
C40H68N2O4S4
Molecular Weight
769.24
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Ma F, et al. Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection. Sci Adv. 2020 Jul 24;6 (30) :eabb4429.|[2]Jia Y, et al. Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy. Adv Mater. 2025 Mar 27:e2500598.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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