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M65 TFA

CAT: 0804-HY-P4127A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P4127A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M65 TFA is a deleted peptide of maxadilan (61 a.a.) with deletion of the residues between positions 24 and 42 and is a specific antagonist of PACAP type 1 receptor that inhibits ANP secretion and can be used for relevant researches[1][2].
UNSPSC
12352209
Target
PACAP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/m65-tfa.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
O=C([C@@H](N)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]3CCC(O)=O)=O)CCCCN)=O)CC4=CC=CC=C4)=O)C(C)C)=O)CO)=O)CC(N)=O)=O)=O)CCC2)=O)C(C)C)=O)CC(N)=O)=O)CO)=O)CC5=CNC=N5)=O)CC6=CNC=N6)=O)C)=O)CCC(N)=O)=O)CCCCN)=O)CCC(N)=O)=O)CSSC[C@H](NC3=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C)=O)CCCCN)=O)CC7=CC=CC=C7)=O)CCC(O)=O)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCC(N)=O)=O)CCCCN)=O)CCSC)=O)=O)CC(O)=O)=O)CC(O)=O)=O)[C@H](CC)C)=O)C)=O)CCCCN)=O)CCCNC(N)=N)=O)CC8=CC=CC=C8)=O)CCC(N)=O)=O)N[C@H](C(N[C@H](C(N[C@H]1[C@@H](C)O)=O)C)=O)CC(O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C205H326N64O61S5.xC2HF3O2
Molecular Weight
4823.53 (free base)
References & Citations
[1]Lerner EA, et al. Maxadilan, a PAC1 receptor agonist from sand flies. Peptides. 2007 Sep;28 (9) :1651-4.|[2]Uchida D, et al. Maxadilan is a specific agonist and its deleted peptide (M65) is a specific antagonist for PACAP type 1 receptor. Ann N Y Acad Sci. 1998 Dec 11;865:253-8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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