JAK3-IN-15

• UNSPSC Description:

  JAK3-IN-15 (compound 22) is a JAK3 inhibitor that reduces LPS-induced p-JAK3 secretion. JAK3-IN-15 can be used in the study of rheumatoid arthritis[1].

• Target Antigen:

  JAK

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/jak3-in-15.html

• Smiles:

  O=C(O[C@]1(C)CC[C@]23[C@H](C)CC[C@@]2([H])C(C)(C)[C@@]1([H])C3)CCN4CCN(S(=O)(C5=CC=CC=C5)=O)CC4

• Molecular Weight:

  502.71

• References & Citations:

  [1]Ma B, et al. Design, synthesis and activity screening of cedrol derivatives as small molecule JAK3 inhibitors. Bioorg Chem. 2024 Nov;152:107762.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported