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AZD8309

CAT: 0804-HY-119259-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119259-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD8309 is an orally active antagonist of CXCR2. AZD8309 has the ability to regulate the transmigration of neutrophils. AZD8309 can be used in the study of inflammatory diseases[1].
CAS Number
333742-48-6
UNSPSC
12352005
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/azd8309.html
Purity
99.98
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1SC2=C(N=C(N=C2N1)SCC3=CC=CC(F)=C3F)N[C@@H](CO)C
Molecular Formula
C15H14F2N4O2S2
Molecular Weight
384.42
References & Citations
[1]Malla SR, et al. Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis. Pancreatology. 2016 Sep-Oct;16 (5) :761-9. |[2]Walters I, Austin C, Austin R, et al. Evaluation of a series of bicyclic CXCR2 antagonists. Bioorg Med Chem Lett. 2008;18 (2) :798-803.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CXCR2

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