AZD8701 (sodium)

• UNSPSC Description:

  AZD8701 (IONIS-1063734) sodium is an antisense oligonucleotide targeting FOXP3 in regulatory T cells (Tregs). AZD8701 sodium can relieve immunosuppression in cancer[1].

• Target Antigen:

  TGF-beta/Smad

• Type:

  Oligonucleotides

• Related Pathways:

  Stem Cell/Wnt;TGF-beta/Smad

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/azd8701-sodium.html

• Smiles:

  [AZD8701 (sodium)]

• References & Citations:

  [1]Alexey Revenko, et al. Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer. J Immunother Cancer. 2022 Apr;10(4):e003892.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1