Sirt2-IN-1

Sirt2-IN-1

• CAS Number: 1862238-00-3
• UNSPSC Description: Sirt2-IN-1 (Compound 9) is a sirtuin 2 (Sirt2) inhibitor with an IC50 of 163 nM[1].
• Target Antigen: Sirtuin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/Sirt2-IN-1.html
• Purity: 98.71
• Solubility: DMSO : 150 mg/mL (ultrasonic)
• Smiles: O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CC4=CC=CC=C4)N=N3)=C2)S1)CSC5=NC(C)=CC(C)=N5
• Molecular Weight: 557.69
• References & Citations: [1]Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin 2. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported