Sirt2-IN-1

• UNSPSC Description:

  Sirt2-IN-1 (Compound 9) is a sirtuin 2 (Sirt2) inhibitor with an IC50 of 163 nM[1].

• Target Antigen:

  Sirtuin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Sirt2-IN-1.html

• Purity:

  98.71

• Solubility:

  DMSO : 150 mg/mL (ultrasonic)

• Smiles:

  O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CC4=CC=CC=C4)N=N3)=C2)S1)CSC5=NC(C)=CC(C)=N5

• Molecular Weight:

  557.69

• References & Citations:

  [1]Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin 2. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1862238-00-3