Products for Research Use Only
RegisterLogin

ACT-1016-0707

CAT: 0804-HY-138453-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-138453-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ACT-1016-0707 (Compound 49) is an orally active and selective LPA1 receptor antagonist. ACT-1016-0707 can be used for the research of fibrotic diseases[1].
CAS Number
2569467-78-1
Product Name Alternative
LPA1 receptor antagonist 2
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/act-1016-0707.html
Purity
98.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1(C2=CC=CC=C2C(C)C)CN(S(=O)(N)=O)C1)NC3=C(OC)C=C(Cl)N=C3
Molecular Formula
C19H23ClN4O4S
Molecular Weight
438.93
References & Citations
[1]Lescop C, et al. Discovery of the Novel, Orally Active, and Selective LPA1 Receptor Antagonist ACT-1016-0707 as a Preclinical Candidate for the Treatment of Fibrotic Diseases. J Med Chem. 2024 Feb 22;67 (4) :2397-2424.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

N-(6-Chloro-4-methoxypyridin-3-yl)-3-(2-isopropylphenyl)-1-sulfamoylazetidine-3-carboxamide
CAS Number2569467-78-1
PubChem CID155412853
IUPAC NameN-(6-chloro-4-methoxy-3-pyridinyl)-3-(2-propan-2-ylphenyl)-1-sulfamoylazetidine-3-carboxamide
Molecular FormulaC19H23ClN4O4S
Molecular Weight438.9
XLogP1.9
Topological Polar Surface Area123
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count29
Formal Charge0
Complexity693
SMILES
CC(C)C1=CC=CC=C1C2(CN(C2)S(=O)(=O)N)C(=O)NC3=CN=C(C=C3OC)Cl
InChI
InChI=1S/C19H23ClN4O4S/c1-12(2)13-6-4-5-7-14(13)19(10-24(11-19)29(21,26)27)18(25)23-15-9-22-17(20)8-16(15)28-3/h4-9,12H,10-11H2,1-3H3,(H,23,25)(H2,21,26,27)
InChIKey
UHFBJBPMIVQTBG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(6-Chloro-4-methoxypyridin-3-yl)-3-(2-isopropylphenyl)-1-sulfamoylazetidine-3-carboxamide
CAS: 2569467-78-1
CID: 155412853
Formula: C19H23ClN4O4S
MW: 438.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight438.9
XLogP31.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass438.1128541
Monoisotopic Mass438.1128541
Topological Polar Surface Area123 Ų
Heavy Atom Count29
Formal Charge0
Complexity693
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-157472ACT-1014-6470
HY-153240ACT-672125
HY-124071-01ACT-389949
HY-101834-01ACT-462206
HY-118036ACT-387042
HY-149055-01ACT-777991
HY-111817-01ACT-451840
HY-108683ACT-335827
HY-135500-01ACT-373898
HY-12616ACT-209905

Alternative Products

CatalogName
E1941-5mgACT-1016-0707
S-310Aroclor 1016
PCB-1016Aroclor 1016 - 1ML
8B0475-AATEGFR (Ab-1016) Antibody
1209818F18743-1016 Round tube rack
YP-W16964-01Human ACT (ACT) ELISA Kit
MBS132402-01Macitentan (ACT 064992; ACT-064992)
PCB-1016HAroclor 1016 (High Level) - 1ML
BA5667-50ACT-462206
BA5321-10ACT-389949

Popular Products