Recombinant Human Chromogranin A

• Description:

  Recombinant Human Chromogranin A

• Product Name Alternative:

  CHGA

• UniProt:

  P10645

• Reactivity:

  Human

• Target Antigen:

  Chromogranin-A

• Target:

  Chromogranin A

• Type:

  Protein

• Applications:

  WB

• Concentration:

  Lot Specific

• Dilution:

  Dilute in PBS or medium that is identical to that used in the assay system.

• Form:

  Liquid

• Buffer:

  20 mM Tris

• Storage Conditions:

  Store at 4°C if entire vial will be used within 2-4 weeks. Store at or below -20°C for longer periods of time. Addition of a carrier protein (such as 0.1% HSA or BSA) is recommended for long-term storage.

• Specificity:

  Chromogranin A

• Formulation:

  Sterile-filtered solution in 20mM Tris-HCl, pH 8.0, and 10% glycerol.

• Buffer pH:

  pH 8.0

• Target Background:

  Chromogranin A (CHGA) is a member of the neuroendocrine secretory protein family located in secretory vesicles of neurons and endocrine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides function as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides including chromostatin, betagranin, WE-14 and GE-25 are also derived from full-length CHGA. CHGA has numerous biological activities including antifungal and antimicrobial action, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.

• CAS Number:

  9000-83-3