Recombinant Human CCL14

• Description:

  Recombinant human CCL14

• Product Name Alternative:

  rHuCCL14, HCC-1

• Gene Name:

  CCL14

• UniProt:

  Q16627

• Cellular Locus:

  Secreted.

• Reactivity:

  Human

• Target Antigen:

  C-C motif chemokine 14

• Target:

  CCL14

• Type:

  Protein

• Applications:

  Migration assay

• Dilution:

  Centrifuge tube prior to resuspending. Recommended at 100ug/ml in sterile distilled water.

• Form:

  Lyophilized

• Function:

  Has weak activities on human monocytes and acts via receptors that also rPubMed:11085751}.

• Additionnal Information:

  Endotoxin Level: <0.01 EU per 1ug of protein by LAL method.Migration Assay in cells expressing CCR1.

• Storage Conditions:

  12 months from date of receipt, -20°C to -70°C, as supplied. 1 month,- 20°C to -70°C, under sterile conditions after reconstitution. Best if used immediately after reconstitution. Avoid multiple freeze-thaw cycles.

• Specificity:

  CCL14

• Target Background:

  CCL14, also known as Hemofiltrate CC Chemokine-1 (HCC-1) is a small cytokine (~8kDa) that is constitutively expressed in multiple tissues. Upon processing of the N-terminal residues of full- length HCC-1 by the uPA-plasmin system, the active form of HCC-1 is a strong agonist for CCR1, CCR5, and, to a lesser extent, CCR3. CCL14 causes chemotaxis of different types of leukocytes, and its active form is a potent inhibitor of HIV entry.

• CAS Number:

  9000-83-3