Echimidine N-oxide

• Description:

  Echimidine N-oxide, a pyrrolizidine alkaloid, has acetylcholinesterase (AChE) inhibitory activity (IC50=0.347 mM) [1].

• UNSPSC:

  12352005

• Hazard Statement:

  H300+H310+H330

• Target:

  Cholinesterase (ChE)

• Type:

  Natural Products

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/echimidine-n-oxide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)(O)[C@@]([C@@H](O)C)(O)C(OCC1=CC[N+]2([O-])[C@@]1([H])[C@@H](CC2)OC(/C(C)=C\C)=O)=O

• Molecular Formula:

  C20H31NO8

• Molecular Weight:

  413.46

• Precautions:

  P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

• References & Citations:

  [1]Houari Benamar, et al. Acetylcholinesterase inhibitory activity of pyrrolizidine alkaloids from Echium confusum Coincy. Nat Prod Res. 2017 Jun;31 (11) :1277-1285.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  AChE

• CAS Number:

  [41093-89-4]