Products for Research Use Only

Tramadol N-oxide

CAT: 0804-HY-105389Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-105389Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tramadol N-oxide (T-N-O) (RWJ 38705) is an analgesic. Tramadol N-oxide sproduces dose-related, long-lasting antinociception in the mouse abdominal irritant, 48 °C hot-plate, 55 °C hot-plate, and tail-flick tests. Tramadol N-oxide has negligible affinity for opioid mu (Ki = 38.5 μM) and delta or kappa receptors (Ki > 100 μM) . Tramadol N-oxide can be used for the study of analgesic effect[1].
CAS Number
147441-56-3
Product Name Alternative
RWJ-38705
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O[C@@]1(C2=CC(OC)=CC=C2)[C@H](CCCC1)CN(C)(C)=O
Molecular Formula
C16H25NO3
Molecular Weight
279.37
References & Citations
[1]Raffa RB, et al. Unexpected antinociceptive effect of the N-oxide (RWJ 38705) of tramadol hydrochloride. J Pharmacol Exp Ther. 1996 Sep;278 (3) :1098-104.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR