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Brucine N-oxide

CAT: 0804-HY-W751355Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W751355Size:1 Each
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Description
Brucine N-oxide is a natural alkaloid isolated from the seeds of Strychnos nux-vomica with analgesic and anti-inflammatory activity. Brucine N-oxide inhibits prostaglandin E2 (PGE2) in Carrageenan -induced rat paw edema and reduces 6-keto-PGF1α in Freund’s complete adjuvant (FCA) (HY-153808) -induced arthritis rat’s blood plasma. Brucine N-oxide can be used for research of diseases associated with pain and inflammation[1].
CAS Number
17301-81-4
UNSPSC
12352005
Hazard Statement
H300-H330
Target
Others
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C1C[C@@]2([H])[C@@]3([H])[C@]4([H])N1C(C=C(C(OC)=C5)OC)=C5[C@]46[C@]7([H])C[C@@]3([H])C(C[N+]7([O-])CC6)=CCO2
Molecular Formula
C23H26N2O5
Molecular Weight
410.46
Precautions
P260-P264-P270-P271-P284-P304+P340-P330-P403+P233-P405-P501
References & Citations
[1]Yin W, et al. Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica. J Ethnopharmacol. 2003 Oct;88 (2-3) :205-14.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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