Procyclidine (hydrochloride)

CAT: 0804-HY-B1487-01Size: 100 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-B1487-01Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Procyclidine (Tricyclamol, (±) -Procyclidine) hydrochloride , an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine hydrochloride can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy[1][2].

CAS Number

1508-76-5

Product Name Alternative

Tricyclamol (hydrochloride) ; (±) -Procyclidine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

IGluR; mAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Procyclidine-hydrochloride.html

Purity

99.55

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCC3.[H]Cl

Molecular Formula

C19H30ClNO

Molecular Weight

323.90

Precautions

H315, H319, H320

References & Citations

[1]Yun-Bae Kim, et al. Effects of combinational prophylactics composed of physostigmine and procyclidine on soman-induced lethality, seizures and brain injuries. Environ Toxicol Pharmacol. 2002 Jan;11 (1) :15-21.|[2]Ulrich Ettinger, et al. Effects of procyclidine on eye movements in schizophrenia. Neuropsychopharmacology. 2003 Dec;28 (12) :2199-208.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

NMDA Receptor

Chemical Information

Procyclidine hydrochloride

Procyclidine Hydrochloride is the hydrochloride salt form of procyclidine, with anticholinergic properties. Procyclidine hydrochloride competitively binds to striatal cholinergic receptors, thereby diminishing acetylcholine activity and ultimately reducing the frequency and severity of akinesia, rigidity, and tremor associated with uncontrollable body movements. In addition, this agent may block the re-uptake of dopamine by nerve terminals, thereby increasing dopamine activity.

CAS Number	1508-76-5
PubChem CID	207841
IUPAC Name	1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride
Molecular Formula	C19H30ClNO
Molecular Weight	323.9
Topological Polar Surface Area	23.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Heavy Atom Count	22
Formal Charge	0
Complexity	301

SMILES

C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl

InChI

InChI=1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H

InChIKey

ZFSPFXJSEHCTTR-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1508-76-5

CID: 207841

Formula: C19H30ClNO

MW: 323.9

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	323.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	323.2015923
Monoisotopic Mass	323.2015923
Topological Polar Surface Area	23.5 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	301
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	2
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-B1487A	Procyclidine
HY-B1487S1	Procyclidine-d5
HY-B0500B	Alverine (hydrochloride)
HY-W714513	VU0469650 (hydrochloride)
HY-W708286-01	α-Pyrrolidinobutiothiophenone (hydrochloride)
HY-W492795	Quifenadine (hydrochloride)
HY-W012179-01	Phenylpiperazine (hydrochloride)
HY-Z6449-01	Phenylephrone (hydrochloride)
HY-W209279	(±) Anabasine (hydrochloride)
HY-W027446-01	Pyridoxal hydrochloride

Alternative Products

Catalog	Name
MBS3609862-01	Procyclidine hydrochloride
TRC-P755842-10MG	Procyclidine-d11 Hydrochloride
CS-O-64659	Procyclidine d5 Hydrochloride
sc-477112	Procyclidine-d8 Hydrochloride
T60578-01	Procyclidine
MBS3842296-01	Procyclidine HCl
A17371-500	Procyclidine HCl 500mg
A17371-25	Procyclidine HCl 25mg
A17371-100	Procyclidine HCl 100mg

Procyclidine (hydrochloride)

Chemical Information

Related Products

Alternative Products

Popular Products