Products for Research Use Only
RegisterLogin

Procyclidine (hydrochloride)

CAT: 0804-HY-B1487-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1487-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Procyclidine (Tricyclamol, (±) -Procyclidine) hydrochloride , an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine hydrochloride can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy[1][2].
CAS Number
1508-76-5
Product Name Alternative
Tricyclamol (hydrochloride) ; (±) -Procyclidine (hydrochloride)
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
IGluR; mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Procyclidine-hydrochloride.html
Purity
99.55
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCC3.[H]Cl
Molecular Formula
C19H30ClNO
Molecular Weight
323.90
Precautions
H315, H319, H320
References & Citations
[1]Yun-Bae Kim, et al. Effects of combinational prophylactics composed of physostigmine and procyclidine on soman-induced lethality, seizures and brain injuries. Environ Toxicol Pharmacol. 2002 Jan;11 (1) :15-21.|[2]Ulrich Ettinger, et al. Effects of procyclidine on eye movements in schizophrenia. Neuropsychopharmacology. 2003 Dec;28 (12) :2199-208.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
NMDA Receptor

Chemical Information

Procyclidine hydrochloride

Procyclidine Hydrochloride is the hydrochloride salt form of procyclidine, with anticholinergic properties. Procyclidine hydrochloride competitively binds to striatal cholinergic receptors, thereby diminishing acetylcholine activity and ultimately reducing the frequency and severity of akinesia, rigidity, and tremor associated with uncontrollable body movements. In addition, this agent may block the re-uptake of dopamine by nerve terminals, thereby increasing dopamine activity.

CAS Number1508-76-5
PubChem CID207841
IUPAC Name1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride
Molecular FormulaC19H30ClNO
Molecular Weight323.9
Topological Polar Surface Area23.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Heavy Atom Count22
Formal Charge0
Complexity301
SMILES
C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl
InChI
InChI=1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H
InChIKey
ZFSPFXJSEHCTTR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Procyclidine hydrochloride
CAS: 1508-76-5
CID: 207841
Formula: C19H30ClNO
MW: 323.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight323.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass323.2015923
Monoisotopic Mass323.2015923
Topological Polar Surface Area23.5 Ų
Heavy Atom Count22
Formal Charge0
Complexity301
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-B1487AProcyclidine
HY-B1487S1Procyclidine-d5
HY-B0500BAlverine (hydrochloride)
HY-W714513VU0469650 (hydrochloride)
HY-W708286-01α-Pyrrolidinobutiothiophenone (hydrochloride)
HY-W492795Quifenadine (hydrochloride)
HY-W012179-01Phenylpiperazine (hydrochloride)
HY-Z6449-01Phenylephrone (hydrochloride)
HY-W209279(±) Anabasine (hydrochloride)
HY-W027446-01Pyridoxal hydrochloride

Alternative Products

CatalogName
MBS3609862-01Procyclidine hydrochloride
TRC-P755842-10MGProcyclidine-d11 Hydrochloride
CS-O-64659Procyclidine d5 Hydrochloride
sc-477112Procyclidine-d8 Hydrochloride
T60578-01Procyclidine
MBS3842296-01Procyclidine HCl
A17371-500Procyclidine HCl 500mg
A17371-25Procyclidine HCl 25mg
A17371-100Procyclidine HCl 100mg

Popular Products