Pyridoxal hydrochloride

• UNSPSC Description:

  Pyridoxal hydrochloride, the hydrochloride form of Pyridoxal (HY-107469), is a newly developed neuroprotective agent. Pyridoxal hydrochloride is one of the major forms of vitamin B6. Pyridoxal hydrochloride is solvolyzed in methanol to form pyridoxal monomethylacetal. Pyridoxal is phosphorylated by pyridoxal kinase to Pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-Pyridoxic acid (HY-113493) which is excreted in the urine. Pyridoxal hydrochloride is proming for research of carpal tunnel syndrome (CTS)[1][2][3].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/pyridoxal-hydrochloride.html

• Purity:

  99.75

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|H2O : 33.33 mg/mL (ultrasonic)

• Smiles:

  O=CC1=C(C=NC(C)=C1O)CO.Cl

• Molecular Weight:

  203.625

• References & Citations:

  [1]Vrolijk MF, et al. The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function[J]. Toxicol In Vitro. 2017 Oct;44:206-212.|[2]Aufiero E, et al. Pyridoxine hydrochloride treatment of carpal tunnel syndrome: a review[J]. Nutr Rev. 2004 Mar;62(3):96-104. |[3]Nagata Y, et al. Solvolysis of pyridoxal hydrochloride in alcohols[J]. Chemical and pharmaceutical bulletin, 1993, 41(6): 1019-1022.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Clinical Information:

  Phase 3

• CAS Number:

  65-22-5