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Procyclidine

CAT: 0804-HY-B1487ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1487ASize:1 Each
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Description
Procyclidine (Tricyclamol; (±) -Procyclidine), an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy[1][2].
CAS Number
77-37-2
Product Name Alternative
Tricyclamol; (±) -Procyclidine
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
IGluR; mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/procyclidine.html
Solubility
10 mM in DMSO
Smiles
OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCC3
Molecular Formula
C19H29NO
Molecular Weight
287.44
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1] Yun-Bae Kim, et al. Effects of combinational prophylactics composed of physostigmine and procyclidine on soman-induced lethality, seizures and brain injuries. Environ Toxicol Pharmacol. 2002 Jan;11 (1) :15-21.|[2]Ulrich Ettinger, et al. Effects of procyclidine on eye movements in schizophrenia. Neuropsychopharmacology. 2003 Dec;28 (12) :2199-208.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
NMDA Receptor

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