Phenoxybenzamine (hydrochloride) (Standard)

Phenoxybenzamine (hydrochloride) (Standard)

• CAS Number: 63-92-3
• UNSPSC Description: Phenoxybenzamine (hydrochloride) (Standard) is the analytical standard of Phenoxybenzamine (hydrochloride). This product is intended for research and analytical applications. Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity[1][2].
• Target Antigen: Adrenergic Receptor
• Type: Reference Standards
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Field of Research: Cancer; Endocrinology; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/phenoxybenzamine-hydrochloride-standard.html
• Smiles: CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl
• Molecular Weight: 340.29
• References & Citations: [1]Habbe N, et al. Urapidil in the preoperative treatment of pheochromocytomas: a safe and cost-effective method. World J Surg. 2013 May;37(5):1141-6.|[2]Lin XB, et al. Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells. Tumour Biol. 2016 Mar;37(3):2901-8.|[3]Rau TF, et al. Phenoxybenzamine is neuroprotective in a rat model of severe traumatic brain injury. Int J Mol Sci. 2014 Jan 20;15(1):1402-17.
• Shipping Conditions: Room temperature