Phenoxybenzamine (hydrochloride)
CAT:
804-HY-B0431A-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Phenoxybenzamine (hydrochloride)
- CAS Number: 63-92-3
- UNSPSC Description: Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity[1][2].
- Target Antigen: Adrenergic Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Cancer-programmed cell death
- Field of Research: Cancer; Endocrinology; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/phenoxybenzamine-hydrochloride.html
- Purity: 98.0
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
- Smiles: CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl
- Molecular Weight: 340.29
- References & Citations: [1]Habbe N, et al. Urapidil in the preoperative treatment of pheochromocytomas: a safe and cost-effective method. World J Surg. 2013 May;37(5):1141-6.|[2]Lin XB, et al. Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells. Tumour Biol. 2016 Mar;37(3):2901-8.|[3]Rau TF, et al. Phenoxybenzamine is neuroprotective in a rat model of severe traumatic brain injury. Int J Mol Sci. 2014 Jan 20;15(1):1402-17.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched