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Bicalutamide-d5

CAT: 0804-HY-14249S1Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14249S1Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bicalutamide-d5 is deuterated labeled Bicalutamide. Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer[1].
UNSPSC
12352005
Target
Androgen Receptor; Autophagy; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Others; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(S(=O)(C([2H])([2H])[C@@](O)(C([2H])([2H])[2H])C(NC2=CC=C(C#N)C(C(F)(F)F)=C2)=O)=O)C=C1
Molecular Formula
C18H9D5F4N2O4S
Molecular Weight
435.40
References & Citations
[1]Nicola J. Clegg,1 John Wongvipat,1,2 Jim Joseph, ARN-509: a novel anti-androgen for prostate cancer treatment. Cancer Res. 2012 March 15; 72 (6) : 1494-1503.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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