Bicalutamide

• Description:

  Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Androgen Receptor; Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy; Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Bicalutamide.html

• Concentration:

  10mM

• Purity:

  99.92

• Solubility:

  DMSO : ≥ 50 mg/mL

• Smiles:

  FC1=CC=C(S(=O)(CC(O)(C(NC2=CC=C(C#N)C(C(F)(F)F)=C2)=O)C)=O)C=C1

• Molecular Formula:

  C18H14F4N2O4S

• Molecular Weight:

  430.37

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Nicola J. Clegg,1 John Wongvipat,1,2 Jim Joseph, ARN-509: a novel anti-androgen for prostate cancer treatment. Cancer Res. 2012 March 15; 72 (6) : 1494-1503.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  90357-06-5