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Bicalutamide-d4

CAT: 0804-HY-14249SSize: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-14249SSize:500 µg
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Description
Bicalutamide-d4 is the deuterium labeled Bicalutamide. Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer[1].
CAS Number
1185035-71-5
UNSPSC
12352005
Target
Androgen Receptor; Autophagy; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C(C)(O)CS(=O)(C2=C([2H])C([2H])=C(F)C([2H])=C2[2H])=O
Molecular Formula
C18H10D4F4N2O4S
Molecular Weight
434.40
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Nicola J. Clegg,1 John Wongvipat,1,2 Jim Joseph, ARN-509: a novel anti-androgen for prostate cancer treatment. Cancer Res. 2012 March 15; 72 (6) : 1494-1503.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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