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FLT3-IN-27

CAT: 0804-HY-168213Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168213Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FLT3-IN-27 (compound 49) is a FLT3-ITD inhibitor with the IC50 of 174 nM. FLT3-IN-27 inhibits cell growth and increases the number of cells in the G1 phase of the cell cycle and can be used for study of acute myeloid leukemia[1].
UNSPSC
12352005
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-in-27.html
Smiles
O=C(NC1=NN=C(SC2=C3C(OC(C4=CC=CC=C4)=C3)=NC=N2)S1)NC5=CC=C(OC)C=C5
Molecular Formula
C22H16N6O3S2
Molecular Weight
476.53
References & Citations
[1]Moradi M, et al. Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors. Eur J Med Chem. 2024 Oct 12;280:116962.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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