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NVP-SAA164

CAT: 0804-HY-15041Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15041Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NVP-SAA164 is an orally active nonpeptide kinin B1 receptor antagonist. NVP-SAA164 reverses CFA (Complete Freund's adjuvant) -induced mechanical hyperalgesia and desArg10KD-induced hyperalgesia in hB1-KI mice, and is inactive in a model of inflammatory pain in wild-type mice[1].
CAS Number
312722-60-4
UNSPSC
12352005
Target
Bradykinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nvp-saa164.html
Smiles
O=C(N1CCOCC1)C2=CC(S(=O)(N3CCC(CC3)C(N4CCN(CC4)C)=O)=O)=CC=C2NCC(C5=CC=CC=C5)C6=CC=CC=C6
Molecular Formula
C36H45N5O5S
Molecular Weight
659.84
References & Citations
[1]Fox A, et al. Antihyperalgesic activity of a novel nonpeptide bradykinin B1 receptor antagonist in transgenic mice expressing the human B1 receptor. Br J Pharmacol. 2005 Apr;144 (7) :889-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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