MG-V-53

• Description :

  MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity[1].

• CAS Number :

  [920157-23-9]

• UNSPSC :

  12352005

• Target :

  VISTA

• Type :

  Reference compound

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mg-v-53.html

• Purity :

  90.0

• Smiles :

  FC1C=CC(C2C=CC(OCCNC(CC3C=CC(F)=CC=3)=O)=NN=2)=CC=1

• Molecular Formula :

  C20H17F2N3O2

• Molecular Weight :

  369.37

• References & Citations :

  [1]Abdel-Rahman SA, et al. Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints. Sci Adv. 2024 Oct 18;10 (42) :eadq5540.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Dedicated for Diverse Library

• Clinical Information :

  No Development Reported