MG-V-53

CAT: 0804-HY-Q25865Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-Q25865Size:1 Each

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Description

MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity[1].

CAS Number

920157-23-9

UNSPSC

12352005

Target

VISTA

Type

Reference compound

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mg-v-53.html

Purity

90.0

Smiles

FC1C=CC(C2C=CC(OCCNC(CC3C=CC(F)=CC=3)=O)=NN=2)=CC=1

Molecular Formula

C20H17F2N3O2

Molecular Weight

369.37

References & Citations

[1]Abdel-Rahman SA, et al. Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints. Sci Adv. 2024 Oct 18;10 (42) :eadq5540.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Dedicated for Diverse Library

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-161412	STR-V-53
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HY-P10982	SjDX5-53
HY-178028	PRMT5-IN-53
HY-177378	HBV-IN-53
HY-162992	NLRP3-IN-53
HY-173184	HDAC6-IN-53
HY-139311-01	YH-53

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T201814-01	MG-V-53
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CRB1000989-01	PMX 53

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