XIAP degrader-1

XIAP degrader-1

• CAS Number: 2803617-91-4
• UNSPSC Description: XIAP degrader-1, a primary amine tethered small molecule, promotes the degradation of X-linked inhibitor of apoptosis protein (XIAP).
• Target Antigen: IAP
• Type: Reference compound
• Related Pathways: Apoptosis
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/xiap-degrader-1.html
• Purity: 99.31
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CN[C@H](C(N[C@@H]1C(N(C2=C(N([C@H]1C)C(CCCCCCCN)=O)C=CC=C2)CC3=C(C=CC=C4)C4=CC=C3OC)=O)=O)C
• Molecular Weight: 587.75
• References & Citations: [1]den Besten W, et al. Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein. J Am Chem Soc. 2021 Jul 21;143(28):10571-10575.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported